cover of episode Your gut’s feelings

Your gut’s feelings

2024/10/16
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Unexplainable

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B
Bird Pinkerton
K
Katerina Johnson
M
Michael Gershon
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Bird Pinkerton: 本期节目探讨了肠道健康与情绪和心理健康之间联系的科学依据,以及相关研究中存在的未解之谜。节目中介绍了相关的研究,包括老鼠实验和人体研究,并探讨了益生菌的作用和局限性。总的来说,节目强调了肠道微生物组对人体生理和心理健康的重要影响,但同时也提醒人们,目前的研究仍处于早期阶段,不能做出过于大胆的结论。 Katerina Johnson: 作为肠道微生物组研究人员,Katerina Johnson 阐述了肠道微生物组的组成和功能,以及它与人体免疫系统、神经系统和激素系统之间的相互作用。她分享了关于肠道微生物组与情绪和行为之间关系的研究结果,包括老鼠实验和人体研究,并讨论了粪菌移植在治疗肠道疾病和改善情绪方面的应用和局限性。她还强调了肠道微生物组多样性的重要性及其与焦虑和社交行为之间的联系。 Michael Gershon: 作为肠神经系统研究的权威,Michael Gershon 介绍了肠神经系统(肠脑)的概念及其与大脑之间的联系。他解释了肠道与大脑之间的信息传递机制,以及肠道微生物组如何通过肠神经系统和迷走神经影响情绪。他强调了肠道中神经递质的作用,以及目前对肠道微生物组与肠脑相互作用机制的了解还很有限。

Deep Dive

Chapters
The gut microbiome, composed of diverse microorganisms, plays a crucial role in human health, interacting with the immune, nervous, and hormonal systems. Some proponents suggest a link between gut health and mental well-being, influencing mood disorders like anxiety and depression.
  • The gut microbiome encompasses various microorganisms residing in the stomach and intestines.
  • These microorganisms aid in digestion, combat harmful bacteria, and interact with bodily systems.
  • Claims suggest the gut microbiome could potentially impact mental health conditions like anxiety and depression.

Shownotes Transcript

How we feel emotionally may be influenced by unseen troves of microbial life that live inside us. Is it possible to harness this gut power? (First published in 2022)

Guests: Michael Gershon), professor of pathology at Columbia University; and Katerina Johnson), microbiome researcher at Oxford University

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