cover of episode The viral ghosts of long Covid

The viral ghosts of long Covid

2021/4/14
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A
Amy Pohl
C
Craig Spencer
J
Julia Belouz
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Julia Belouz:长期新冠患者人数众多,症状复杂多样,且病因不明。许多患者的症状与感染埃博拉病毒的患者相似,这表明长期症状并非新冠病毒独有。历史上许多病毒感染都曾导致部分患者出现长期症状,这提示长期症状可能是病毒感染的常见现象,而非某种新疾病。医学上无法解释的症状是一个广泛的范畴,包括慢性莱姆病、慢性疲劳综合征等,这些疾病都与感染有关,但病因不明。 Amy Pohl:长期新冠的潜在病因可能包括病毒残留、其他病毒激活和免疫系统异常等。病毒可能残留在体内组织中(病毒库),即使常规检测呈阴性,也可能持续引起炎症和症状。新冠病毒感染可能激活体内其他休眠病毒,导致症状加重。免疫系统也可能攻击自身组织,造成炎症和长期症状。此外,病毒可能造成器官损伤或肠道菌群失衡,导致长期症状。这些病因可能也适用于其他医学上无法解释的长期症状。 Craig Spencer:许多长期新冠患者被医生误诊或忽视,他们需要得到更多的关注和重视。 Julia Belouz:新冠疫苗对部分长期新冠患者有效,但并非所有患者都有效。目前医学实践难以应对医学上无法解释的长期症状,需要个性化治疗方案。重视患者的主观感受,而非仅仅依赖客观检查结果,对诊断和治疗至关重要。医学界对长期症状的忽视,尤其体现在对女性患者的误诊上。

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Discusses the prevalence and impact of long-haul symptoms in COVID-19 patients, affecting an estimated 10% of cases, or over 12 million people globally.

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Scientists don’t understand why so many people suffer from Covid-19 symptoms for months, well after they stop testing positive. But that’s just the start of the mystery. There are other diseases that cast these long shadows, and they point to a major blind spot in medicine.

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