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#270 ‒ Journal club with Andrew Huberman: metformin as a geroprotective drug, the power of belief, and how to read scientific papers

2023/9/11

The Peter Attia Drive

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#270 ‒ Journal club with Andrew Huberman: metformin as a geroprotective drug, the power of belief, and how to read scientific papers

The Peter Attia Drive

Chapters

What motivated the journal club conversation?

Why did Peter choose a paper on metformin?

What is insulin resistance and what causes it?

Metformin as a first-line treatment for type 2 diabetes

Defining 'geroprotection'

The 2014 study that sparked interest in metformin as a geroprotective drug

Peter presents the 2022 paper on metformin

How did the results differ between the 2022 and 2014 metformin studies?

Understanding statistical significance in epidemiology

Key takeaways from the 2022 metformin study

Current thoughts on metformin for longevity

Could short periods of caloric restriction offer longevity benefits?

Peter and Andrew's approach to reading scientific papers

How do 'belief effects' differ from placebo effects?

The neurobiology of nicotine

Andrew presents a paper on the impact of belief

Analyzing the results of the Perl paper

Exciting implications of the 'belief' findings

Shownotes Transcript

#270 ‒ Journal club with Andrew Huberman: metformin as a geroprotective drug, the power of belief, and how to read scientific papers 02:16:58 Share

The Peter Attia Drive

Chapters

What motivated the journal club conversation?

Why did Peter choose a paper on metformin?

What is insulin resistance and what causes it?

Metformin as a first-line treatment for type 2 diabetes

Defining 'geroprotection'

The 2014 study that sparked interest in metformin as a geroprotective drug

Peter presents the 2022 paper on metformin

How did the results differ between the 2022 and 2014 metformin studies?

Understanding statistical significance in epidemiology

Key takeaways from the 2022 metformin study

Current thoughts on metformin for longevity

Could short periods of caloric restriction offer longevity benefits?

Peter and Andrew's approach to reading scientific papers

How do 'belief effects' differ from placebo effects?

The neurobiology of nicotine

Andrew presents a paper on the impact of belief

Analyzing the results of the Perl paper

Exciting implications of the 'belief' findings

Shownotes Transcript

#270 ‒ Journal club with Andrew Huberman: metformin as a geroprotective drug, the power of belief, and how to read scientific papers