cover of episode What really helps with hangovers?

What really helps with hangovers?

2024/12/3
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Science Weekly

People
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Madeleine Finlay
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Miracle
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Sally Adams
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SureShot
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Zbiotics
Topics
Madeleine Finlay: 本期节目探讨了宿醉的科学原理,以及各种预防和治疗宿醉的方法,包括药物和生活方式的改变。采访了酒精研究专家Sally Adams博士,讨论了宿醉的成因、症状和目前市面上声称可以预防或治疗宿醉产品的有效性。 节目中还讨论了宿醉的定义和研究的挑战,以及一些预防宿醉的常见方法,例如多喝水、补充电解质和进食等。 最后,节目总结了目前市面上声称可以预防或治疗宿醉产品的科学依据,指出这些产品大多缺乏充分的临床证据支持其有效性。 Sally Adams: 宿醉是饮酒后出现的生理和心理症状的组合,包括头痛、恶心、呕吐、情绪低落和焦虑等。宿醉不仅仅是脱水,还包括身体分解酒精的过程。身体将酒精转化为乙醛,这是一种有毒化学物质,会导致恶心和呕吐。酒精还会影响神经递质(GABA、多巴胺和血清素)的平衡,导致第二天情绪低落和焦虑。 目前关于宿醉的研究还比较有限,主要是因为难以测量和捕捉宿醉症状,以及参与者参与研究的意愿。此外,宿醉研究还存在伦理问题,例如让参与者喝醉酒。 一些产品声称可以通过减少酒精吸收或分解乙醛来预防或缓解宿醉,但目前关于这些产品的证据不足,研究样本量小,缺乏对宿醉症状的全面评估。与药物相比,这些产品不需要经过严格的测试。 一些预防宿醉的方法有一定的科学依据,例如补水、补充电解质和进食。但没有一种方法可以完全预防宿醉。 Zbiotics: Zbiotics产品声称通过分解乙醛来缓解宿醉症状,并有较高的顾客满意度。 SureShot: SureShot产品声称经过临床验证,可以快速有效地降低血液酒精含量,减少毒素,改善身心健康。 Miracle: Miracle产品声称可以降低酒精在血液中的吸收率。

Deep Dive

Key Insights

What is a hangover, scientifically speaking?

A hangover is a combination of psychological and physiological symptoms experienced after drinking, when blood alcohol concentration is close to or has returned to zero. Symptoms include headache, nausea, vomiting, low mood, anxiety, and impaired decision-making.

What are the main physiological effects of alcohol that contribute to hangovers?

Alcohol is converted into acetaldehyde, a toxic chemical that causes nausea and sickness. It also leads to changes in blood sugar, inflammation in the stomach and small intestine, and affects neurotransmitters like GABA, dopamine, and serotonin, which can cause low mood and anxiety.

Why is hangover research challenging for scientists?

Hangover research is challenging because it's difficult to measure hangover symptoms accurately, as people must have no alcohol left in their system. Additionally, people are reluctant to participate in hangover studies, and hangovers are often seen as trivial, receiving less attention than other alcohol-related research.

What do products like Miracle and SureShot claim to do, and how do they propose to work?

Miracle and SureShot are probiotics that claim to reduce alcohol absorption and support alcohol metabolism. Miracle contains Bacillus coagulans and L-cysteine, while SureShot claims to break down alcohol into water and carbon dioxide and replenish electrolytes.

What is the scientific evidence for these hangover prevention products?

The evidence for these products is limited. Studies are often based on animal models or small human trials, and they focus on changes in alcohol absorption rather than observable effects on hangover symptoms. These products, marketed as nutritional supplements, do not undergo the same rigorous testing as medications.

What are some effective methods to reduce hangover symptoms?

Effective methods to reduce hangover symptoms include rehydrating with water and electrolyte solutions, eating fatty foods before drinking to slow alcohol absorption, and taking B vitamins. However, there is no single miracle cure that can target all aspects of a hangover.

Chapters
This chapter explores the scientific understanding of hangovers, highlighting the lack of extensive research compared to intoxication studies. It discusses the difficulties in measuring hangovers and the ethical considerations of hangover research.
  • Hangovers are a combination of psychological and physiological symptoms experienced after drinking, even when blood alcohol concentration is zero.
  • Research on hangovers lags behind research on intoxication.
  • It's difficult to measure hangovers and recruit participants for hangover studies.

Shownotes Transcript

What if you could take a pill or a shot that could reduce your blood alcohol level and make you feel better in the morning? That’s the promise of a range of wellness products aiming to be the next big hangover antidote. But what exactly are hangovers, and which methods of preventing them are backed by science? Madeleine Finlay speaks to Dr Sally Adams, an alcohol researcher and associate professor of psychology at the University of Birmingham. Help support our independent journalism at theguardian.com/sciencepod)