cover of episode The Interstitium

The Interstitium

2023/11/17
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D
David Carlock
J
Jen Brandel
L
Lulu Miller
N
Neil Theis
P
Peter Friedl
Q
Quxing Chen
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Neil Theis: 本人选择从医的经历,以及对间质研究的意外发现和最初的质疑。他回顾了自己从医的初衷,以及在研究中如何克服偏见和质疑,最终发现并命名间质的过程。他强调了科学发现中克服固有偏见的重要性,以及开放心态在科学探索中的作用。 David Carlock: 使用新型内窥镜技术观察到间质的经历,以及对间质结构的初步描述。他详细描述了新型内窥镜的优势,以及在使用该技术观察活体组织时,意外发现间质的过程。他强调了新技术在医学发现中的作用,以及对传统医学观念的挑战。 Lulu Miller & Jen Brandel: 间质的发现及其对人体结构和功能的意义。她们对间质的发现过程进行了详细的回顾,并对间质的结构和功能进行了深入的探讨。她们还探讨了间质在不同器官中的分布和作用,以及间质研究对医学和社会的影响。 Quxing Chen: 针灸治疗与间质结构的关系,以及在动物实验中观察到的间质细胞的激活现象。他详细描述了他在动物实验中观察到的现象,以及对间质细胞功能的推测。他强调了东西方医学的融合,以及对传统医学理论的重新审视。 Peter Friedl: 间质结构与癌症转移的关系,以及利用间质通道进行癌症治疗的新策略。他详细描述了癌症转移的机制,以及他如何利用间质结构来开发新的癌症治疗方法。他强调了基础研究在医学发展中的重要性,以及对传统癌症治疗方法的挑战。

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In this episode we introduce you to a part of our bodies that was invisible to Western scientists until about five years ago; it’s called "the interstitium," a vast network of fluid channels inside the tissues around our organs that scientists have just begun to see, name, and understand. Along the way we look at how new technologies rub up against long-standing beliefs, and how millions of scientists and doctors failed to see what was right in front (and inside!) of their noses. We also find out how mapping the anatomy of this hidden infrastructure may help solve one of the fundamental mysteries of cancer, and perhaps provide a bridge between ancient and modern medicine.Special thanks to Aaron Wickenden, Jessica Clark, Mara Zepeda, Darryl Holliday, Dr. Amy Chang, Kate Sassoon, Guy Huntley, John Jacobson, Scotty G, and the Village Zendo

EPISODE CREDITS - 

Reported by - Lulu Miller and Jenn BrandelProduced by - Matt Kieltywith help from - Ekedi Fausther-Keeyswith mixing help from - Arianne WackFact-checking by - Natalie Middletonand Edited by  - Alex Neason

EPISODE CITATIONS -

Articles: Check out reporter Jenn Brandel’s companion essay to this episode in Orion magazine, titled, Invisible Landscapes) (https://zpr.io/NKuxvYY84RvH)), which argues that the discovery of the interstitium could challenge established practices of compartmentalizing in science and society.*Our newsletter comes out every Wednesday. It includes short essays, recommendations, and details about other ways to interact with the show. Sign up) (https://radiolab.org/newsletter)!**Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab) (https://members.radiolab.org/) today.*Follow our show on Instagram), Twitter) and Facebook) @radiolab, and share your thoughts with us by emailing [email protected]).

Leadership support for Radiolab’s science programming is provided by the Gordon and Betty Moore Foundation, Science Sandbox, a Simons Foundation Initiative, and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.