Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2023.04.15.536993v1?rss=1
Authors: Bryant, P., Noe, F.
Abstract:
AlphaFold2 (AF) can evaluate protein-protein interactions (PPIs) with high accuracy by finding evolutionary signals between proteins but comes with a high computational cost. Here, we speed up the prediction with AF for PPI network prediction 40x and reduce the disk space requirements 4000x for a set of 1000 proteins. Our protocol is easy to install and freely available from: https://github.com/patrickbryant1/SpeedPPI.
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