cover of episode macrosyntR : Drawing automatically ordered Oxford Grids from standard genomic files in R

macrosyntR : Drawing automatically ordered Oxford Grids from standard genomic files in R

2023/1/27
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PaperPlayer biorxiv bioinformatics

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Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.01.26.525673v1?rss=1

Authors: El Hilali, S., Copley, R. R.

Abstract: Macrosynteny refers to the conservation of chromosomal to sub-chromosomal domains across species and its conservation can provide insight on the evolution of animal genomes. Pairwise comparison of de-novo assembled genomes based on predicted protein sequences often use a graphical visualization called an Oxford grid. We implemented an R package to draw Oxford grids from standard genomic file formats. The package can automatically order the chromosomes, to improve interpretability, and is thus helpful for both exploratory data analysis and production of publication quality graphics.

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