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Healio Rheuminations
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NSAIDs, Part 3: The rise, fall and rise again of COX-2 inhibition
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2024/8/29
Healio Rheuminations
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Chapters
Intro
Recap of Part 1 & 2
What's in Store for This Episode?
Cyclooxygenase 2 (COX-2) and the Rat Experiment
What Do We Know About Prostaglandins and COX-2?
What Does Prostacyclin Do?
The First COX-2 Inhibitor: VIOXX
What Is COX-2 Doing? Insights from Pfizer and Merck
Two More NSAID Studies: Colon Cancer, Alzheimer’s Disease, and COX-2 Inhibitors
VIOXX: Why Is Myocardial Infarction Risk Occurring?
Animal Models and the Goldilocks Theory of Thromboxane and Prostacyclin
The PRECISION Trial: What Did It Reveal?
Rheum + Boards
Shownotes
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