cover of episode Recap: The misunderstood function of fat | Deborah Clegg

Recap: The misunderstood function of fat | Deborah Clegg

2025/2/11
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Sarah Berry
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@Deborah Clegg : 我认为身体脂肪对健康至关重要,过少和过多都不利。女性需要足够的脂肪才能怀孕,而且脂肪实际上是一个内分泌器官,分泌有益的激素。健康的脂肪细胞像氨纶一样具有扩张能力,而不健康的脂肪细胞则被结缔组织包裹,无法扩张,导致卡路里进入肝脏或心脏等不该去的地方。男女的身体脂肪分布不同,女性倾向于将脂肪储存在臀部和大腿,且这种储存方式是健康的,而男性倾向于将脂肪储存在腹部区域,以便快速利用能量。但是男性腹部的脂肪不宜过多,过多的腹部脂肪是不健康的。男性比女性更容易减肥,因为女性的身体设计是为了储存额外的卡路里。臀部和大腿的脂肪是健康的脂肪。面对身体脂肪分布的变化,要保持宽容,注意饮食和锻炼。增加肌肉可以提高代谢率,建议进行负重活动并变换锻炼方式。应该更加注重饮食,避免食用过度加工的食物,食用加工食品即使摄入相同卡路里,也比食用非加工食品更不健康。应该回归更健康的饮食,选择新鲜水果和蔬菜,自己烹饪或确保使用新鲜食材。 @Sarah Berry : 我认为绝经后女性对富含碳水化合物的食物血糖反应更高,因此应注意饮食类型,减少精制碳水化合物的摄入。

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This chapter explores the fundamental nature of body fat, its role as an energy reserve, and its endocrine function. It challenges the misconception that all fat is bad and highlights the importance of body fat for both men and women's health.
  • Body fat is stored in adipocytes (fat cells).
  • Insufficient body fat can be detrimental to health.
  • Body fat acts as an endocrine organ, secreting hormones.
  • Healthy fat cells can expand to store calories, unlike unhealthy fat cells which are encased in connective tissue.

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Hello and welcome to Zoe Recap, where each week we find the best bits from one of our podcast episodes to help you improve your health.

Today we're discussing fat. It's a word that carries a lot of weight. It's a source of social judgment, a driver of insecurities, and a tool exploited by big food companies in targeted marketing campaigns. It's no surprise that a recent study found over 40% of people in the US have experienced some form of fat shaming. But do we really understand fat? What it does? How it forms? And why its distribution changes as we age?

Professor Sarah Berry and Dr. Deborah Clegg are here to help us answer some of these questions and change our perception of fat. What is body fat?

Oh, that's a great question, right? So as we eat, extra calories or even calories that we eat have to be stored somewhere. And so it's actually stored in a fat cell. We call it an adipocyte. It's a science-y term to talk about a fat cell. And that's where calories are stored. So if you don't have enough body fat, it's actually as detrimental to your health as if you have too much.

Because you don't have the energy that you might need. Exactly, right? It's absolutely critical. And women, it's even more critical. Our brain somehow registers how much fat we have. If we don't have enough fat, we won't be able to become pregnant. So it's really, really important to understand how incredibly wonderful body fat actually is. I think it's also something that, again, we think of it as being bad, but now we've discovered that it's like an endocrine organ. It actually secretes all of these wonderful hormones. Right.

It's really, really important for our health. And I'm quite surprised to hear that because I sort of think of fat as being this completely inert thing that we're carrying around. And I heard you say it's a store of energy. So I sort of understood that because it's a bit like, you know, when you're eating food, right? We know that fat and carbohydrate are these sort of simple macronutrients.

You're saying that it's not as simple as that? It's not, because I think there are so many different ways in which fat is regulated that we don't often pay attention to. So it does store calories, but it also secretes hormones.

And I think that the idea that all fat is bad is a misconception. There are fat cells that can be healthy, and women tend to have more of those healthy fat cells than men. So even when you were asking your questions, you were utilizing yourself as, you know, in me. I might have responded differently if she were asking those exact same questions. So that's interesting. So what is healthy fat then?

I think healthy fat is the type of fat, I love to call it spandex, right? So if you think of a fat cell, it's sort of basically a circle. And a healthy fat cell has the ability to expand when you have extra calories that you're taking in and need to be stored. An unhealthy fat cell is one that I think of as wool. It's a circle, but it's encased in connective tissue or fibers, and it has no ability to expand.

And so all those extra calories, instead of being stored in that fat cell, actually go into your liver or into your heart, go into places that are not supposed to be. And that's when it becomes very unhealthy. So what changes a healthy fat cell to an unhealthy fat cell and vice versa? Is it reversible? It's not necessarily reversible. It's a

Great question. But what a healthy fat cell is, is one that has this expandable capacity. And what makes it that way? Estrogen is one of the items that actually makes a healthy fat cell healthy. Men have estrogen as well. Oftentimes we forget that men have estrogen. And so it's really the sort of the level of estrogens to testosterone that is so critical. But estrogens make this beautiful, expandable, spandex-y-like fat cell.

And so is body fat the same in males and females? No, it's very different, right? And I like to think back to why that might be. And I think it has to do with the fact that women, when we gain weight, and we have to gain weight in a really, really healthy fashion, our bodies are designed to do that, we store those extra calories in our hips and thighs in these beautiful spandex-like fat cells.

Men, on the other hand, store their fat predominantly in their belly area. The overall design back in the hunter-gatherer days was that the men predominantly were out there chasing the wild game. And so they had to store a little bit of fat so they would have energy to be able to chase prey.

bring in the food. And so they would store a little bit of fat in their abdominal area because you could utilize that fat really, really quickly. And so that's where men store fat, where women put it in our hips and thighs, and it's bloody difficult to get rid of from our hips and thighs. But the women's fat is in this really protective area. And then during breastfeeding, we mobilize the calories that are in those fat stores to support the calories that we expend for breastfeeding.

And so, well, you're saying that as a woman, you're storing your fat in an area which you're describing spandex as like it's quite easy to expand this and it's not interfering with any of the organs that are important for my health and that that might be related to things like breastfeeding where you're having to get a lot of calories. I've seen this, right? You get a lot of calories for your children. Yeah.

Whereas men are storing this for whatever the biological underlying reason or evolutionary reason might be, they're storing it around their belly, tucked in with all sorts of organs, which I can think of the liver, but I'm sure you can tell me lots of others that are down there. And that is much more constrained.

Yes, exactly. So those fat cells, you wouldn't want them to get too big, right? Because then all of a sudden, well, you see that now in aging men. You see big, big bellies, right? That's not what we wanted. We wanted to be able to mobilize a very small amount of extra calories that are stored in those fat cells for hunter-gathering days, right? And what's really fascinating to me is that if you have a male and a female, same age, they both go on the same diet,

the man will lose weight faster than the female. Again, because we are designed to gain weight and we hold on to those extra calories as much as we can. And so oftentimes I can talk to a man and a woman and they've gone on the diet together and the man will lose weight and all of a sudden he can cinch his belt up a little quicker, a little easier. It's like he's moved a notch on his belt where the woman is still struggling because she's still got those hips and thighs. And again, it's really, really difficult to mobilize that.

But again, we have to embrace it because those are the really healthy fat cells, the ones that are in our hips and thighs. And so, Debbie, you've said how the fat cells are different around your stomach versus your hips and thighs and how men might be able to lose the fat more quickly than females. What about within a female? Where can you lose it from more quickly? Is it more stubborn around the belly because of these differences? It is a little bit more stubborn, especially as we age. But we'll go with someone who is

premenopausal. And so what happens is that typically we love to store, again, the calories in our hips and thighs. But once we've hit storage capacity such that the spandex has expanded as much as it possibly can, then we start to store it in other places, and that's when it starts to go to your belly. And

And so that's also when it starts to become less healthy. And then again, that's in the premenopausal stage. I like to think of it as sort of their storage tanks. So you first fill up your storage tank, which is your hips and thighs. And then once those tanks are completely full, then it starts to shift in women into that belly area. And that's when we have a higher incidence of diseases such as diabetes, cardiovascular disease, even some cancers.

The largest number of questions we had from our community were actually saying, once I've been experiencing basically this shift in where my body fat is distributed, what can I do about it? Well, I think first of all, being forgiving. Understand that it's a natural biological shift. I think also making sure that we're eating right and still doing our exercise. I think that that is important.

The health message doesn't really change. I think it just becomes more important because I... And does the exercise have an impact on... Absolutely. ...on this? And that really does affect sort of the redistributing because I think lots of people will be listening to this and potentially, you know, a bit surprised that that makes any difference to your fat distribution rather than just impact your health. I would say that you're still going to have a shift. It's still going to happen, right? But I think that what the exercise does is it helps maintain our muscle mass and...

And the more muscle we have, the higher our metabolic rate. So I just am a huge advocate of weight-bearing activity. I also love for people to switch it up. Don't just get stuck in the same routine, right? You know, I think that our bodies are such incredible machines. They get very, very comfortable with one activity. You know, so if you only go to the treadmill and every day you run for an hour on the treadmill, now maybe as you're starting to transition, mix it up a bit.

And I think something, Jonathan and Debbie, that I get asked a lot is what foods can I change? But what we do know from our own research is that how you metabolize the food is actually quite different depending on the phase of your menopause, whether you're pre or post menopause. So what we find is that postmenopausal women who we know are more insulin resistant actually have a higher blood sugar response to a carbohydrate rich meal.

And so one recommendation we can make, given that we know that that's not best for our health, we can say, actually, can you be a bit more mindful about the types of food that you're eating? So be a bit more mindful about having refined carbohydrates. So your white breads, your white pastas, your white rice, you know, your sugary foods. So whilst there is no silver bullet, I think it's really important.

a time that we can say, yeah, just be a bit more mindful about those kind of quick fix foods. I love that. I think that being more mindful is spot on. I think the other thing too is that oftentimes we reach for really refined foods, you know, the processed foods.

And there's so much data coming out right now indicating that processing of foods, even if you eat the same number of calories, but all of your calories are coming from processed foods, it's so much more unhealthy, the processed foods. So I think that as we transition, if we can go back

and eat a more healthy diet that is not processed. Going for the fresh fruits and vegetables, actually making your meals either at home or making certain that you're utilizing fresh ingredients will do a world of good, especially as we're transitioning. I think that's the most important message for people to take home is that actually enjoy cooking again. ♪

That's it for this week's recap. If you're hearing this, you're already on your way to making smarter food choices with world-leading science. Speaking of making smarter food choices, Zoe membership helps you to do just that with scientific solutions that let you listen to your gut. Listening to your gut starts with an at-home test kit that helps you understand your body's responses to food and the good and bad microbes in your gut. Then Zoe's app helps you build life-changing nutrition habits step by step.

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