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cover of episode Dr. Noam Sobel: How Smells Influence Our Hormones, Health & Behavior

Dr. Noam Sobel: How Smells Influence Our Hormones, Health & Behavior

2023/5/1
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Dr. Sobel discusses the incredible power of the human sense of smell and how it compares to other mammals. He highlights the remarkable detection threshold of humans, citing examples like mercaptans in cooking gas and estratetraenol, showcasing our ability to detect minute concentrations of odorants. The conversation then delves into the structure of the olfactory system, starting from the olfactory epithelium with millions of receptors to the olfactory bulb in the brain, where signals are processed and relayed to other brain regions.

Shownotes Transcript

In this episode, my guest is Noam Sobel, PhD, professor of neurobiology in the department of brain sciences at the Weizmann Institute of Science. Dr. Sobel explains his lab’s research on the biological mechanisms of smell (“olfaction”) and how sensing odorants and chemicals in our environment impacts human behavior, cognition, social connections, and hormones. He explains how smell is a crucial component of “social sensing” and how we use olfaction when meeting new people to determine things about their physiology and psychology, and he explains how this impacts friendships and romantic partners. He explains how smell influences emotions, hormone levels, memories and the relationship between breathing and autonomic homeostasis. He describes how smell-based screening tests can aid disease diagnosis and explains his lab’s work on digitization of smell — which may soon allow online communication to include “sending of odors” via the internet. Dr. Sobel’s work illustrates how sensitive human olfaction is and how it drives much of our biology and behavior.

For the full show notes, visit hubermanlab.com).

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Timestamps

(00:00:00) Dr. Noam Sobel

(00:04:03) Sponsors: LMNT & Waking Up

(00:06:46) Olfaction Circuits (Smell)

(00:14:49) Loss & Regeneration of Smell, Illness

(00:21:39) Brain Processing of Smell

(00:24:40) Smell & Memories

(00:25:11) Sponsor: AG1

(00:29:07) Humans & Odor Tracking

(00:39:25) The Alternating Nasal Cycle & Autonomic Nervous System

(00:48:18) Cognitive Processing & Breathing

(00:54:47) Neurodegenerative Diseases & Olfaction

(01:00:12) Congenital Anosmia

(01:06:19) Handshaking, Sharing Chemicals & Social Sensing

(01:15:07) Smelling Ourselves & Smelling Others

(01:22:02) Odors & Romantic Attraction

(01:24:58) Vomeronasal Organ, “Bruce Effect” & Miscarriage

(01:40:20) Social Chemo-Signals, Fear

(01:50:26) Chemo-Signaling, Aggression & Offspring

(02:03:57) Menstrual Cycle Synchronization

(02:12:11) Sweat, Tears, Emotions & Testosterone

(02:27:46) Science Politics

(02:37:54) Food Odors & Nutritional Value

(02:45:34) Human Perception & Odorant Similarity

(02:52:12) Digitizing Smell, COVID-19 & Smell

(03:05:50) Medical Diagnostic Future & Olfaction Digitization

(03:10:55) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac)

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