cover of episode Introducing PandaNovo for practical large-scale de novo peptide sequencing

Introducing PandaNovo for practical large-scale de novo peptide sequencing

2023/7/16
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PaperPlayer biorxiv bioinformatics

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Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.15.549133v1?rss=1

Authors: Yang, T., Ling, T., Sun, B., Liang, Z., Xu, F., Huang, X., Xie, L., He, Y., Li, L., He, F., Wang, Y., Chang, C.

Abstract: De novo peptide sequencing is a promising approach for novel peptide discovery. We use a novel concept of complementary spectra to enhance ion information and propose a de novo sequencing model PandaNovo based on Transformer architecture. PandaNovo outperforms other state-of-the-art models and enhances the taxonomic resolution of gut metaproteome, taking a significant step forward in de novo sequencing.

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