Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2023.04.06.535947v1?rss=1
Authors: Wimley, W. C., Hristova, K.
Abstract:
We present a simple, spreadsheet-based method to determine the statistical significance of the difference between any two arbitrary curves. This modified Chi-squared approach includes a critical correction for the deviation from normality in measurements with small sample size, which are typical in biomedical sciences. Statistical significance is determined without regard to the functionality of the curves, or the signs of the differences. Numerical simulations are used to validate the procedure, and example experimental data are used to demonstrate its application.
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