Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2023.04.21.537877v1?rss=1
Authors: Haldar, A. N., Oza, V. H., DeVoss, N. S., Clark, A. D., Lasseigne, B. N.
Abstract:
High throughput sequencing technologies have enabled cross-species comparative transcriptomic studies; however, there are numerous challenges for these studies due to biological and technical factors. We developed CoSIA (Cross-Species Investigation and Analysis), an Bioconductor R package and Shiny app that provides an alternative framework for cross-species transcriptomic comparison of non-diseased wild-type RNA sequencing gene expression data across tissues and species through visualization of variability, diversity, and specificity metrics.
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