cover of episode Census: accurate, automated, deep, fast, and hierarchical scRNA-seq cell-type annotation

Census: accurate, automated, deep, fast, and hierarchical scRNA-seq cell-type annotation

2022/10/21
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PaperPlayer biorxiv bioinformatics

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Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.19.512926v1?rss=1

Authors: Ghaddar, B., De, S.

Abstract: We developed Census, an automated, hierarchical cell-type identification method for scRNA-seq data that can deeply annotate normal cells in mammalian tissues and identify malignant cells and their likely cell of origin. When benchmarked on 44 atlas-scale normal and cancer, human and mouse tissues, Census significantly outperforms state-of-the-art methods across multiple metrics. Census is a fast and fully automated method, although users can seamlessly train their own models for customized applications.

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