In this episode of The Skin Science Podcast, Thomas M. Hitchcock, Ph.D., Chief Science Officer, speaks with Jigna Patel, MD, of Vedaskin, and Angela Wilson McDonald, Global VP, Education and Customer Success, about retinoids and their impact on the skin's microbiota. The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.0:00 Intro1:06 Special guest, Dr. Jigna Patel4:57 Holistic approaches6:10 Retinoids & patient considerations10:12 Safety concerns13:40 What do retinoids do?18:29 Changing approaches to skincare21:06 Do modern societal norms accelerate aging?25:25 Accepting progression in skincare31:55 Intermission for puzzle of the day35:28 How Xycrobe technology came to be43:50 Using commensal microbes for better skin health48:20 Translating science into patient care53:59 C. acnes and retinoid receptors56:50 Closing remarks