Proceedings from a daylong symposium hosted in partnership with Medical Oncology Association of Southern California, featuring key clinical presentations and papers in acute myeloid leukemia and myelodysplastic syndromes, breast cancer, chronic lymphocytic leukemia and lymphomas, gastrointestinal cancers, genitourinary cancers, lung cancer and multiple myeloma. Featuring perspectives from Drs Kenneth C Anderson, Joaquim Bellmunt, D Ross Camidge, Harry Paul Erba, Rami Komrokji, Benjamin Levy, Wells A Messersmith, Craig Moskowitz, Ruth O’Regan, Eileen M O’Reilly, Sumanta Kumar Pal, Noopur Raje, Jeff Sharman and Tiffany A Traina, moderated by Dr Neil Love.