The gut microbiome is considered a 'sixth sense' because it interacts with everything in your environment, influencing your health and well-being. It communicates with your immune system, affects brain function, and plays a crucial role in digestion and metabolism.
The loss of biodiversity in the gut microbiome is compared to an internal climate crisis because it can have significant health implications. The biodiversity of these microbial ecosystems is crucial for maintaining health, and its erosion can lead to various diseases and conditions.
The gut microbiome includes archaea, yeasts, worms, and viruses. While bacteria are the most studied, other components like viruses (the virome) are increasingly recognized as important players, with about 150,000 species of viruses in the gut, none of which are well understood.
The gut microbiome develops from a sterile state in the womb to a diverse ecosystem through contact with the birth canal, breastfeeding, and the environment. It changes significantly in early life, stabilizes in adulthood, and becomes more vulnerable to changes in old age.
Diet is a critical factor because it directly influences the types and functions of gut microbes. A Western diet high in processed foods can reduce microbial diversity, while a high-fiber diet, like that of rural Africans, can promote a diverse and healthy microbiome.
The gut microbiome teaches the immune system to distinguish between friend and foe, particularly the adaptive immune system. It communicates with the immune system through molecular languages, affecting the risk of allergies, asthma, and other immune-related conditions.
A fecal microbiota transplantation (FMT) involves transferring a healthy donor's gut microbiome to a patient. It can be life-saving for conditions like Clostridium difficile infection by resetting the gut ecosystem and creating competition for harmful bacteria.
The gut microbiome influences mental health by producing neurotransmitter precursors, affecting brain development and function, and communicating with the brain through the vagus nerve and enteric nervous system. A healthy microbiome is essential for a healthy mind.
The gut microbiome can affect attractiveness by influencing skin health, pheromones, and social cues. Kissing, for example, transfers about 80 million bacteria, which can help optimize the microbiome and share beneficial genes.
To maintain a healthy gut microbiome, avoid unnecessary antibiotics, reduce reliance on polypharmacy, get vaccinated, eat a fiber-rich diet, and share meals with others. Adding just 7 grams of fiber per day can lower your risk of stroke.
Ian Sample speaks to colorectal surgeon and researcher James Kinross about the miraculous world of our gut microbiome, how modern life is impacting it, and what we can do to look after it Because of industrial action taking place by members of the National Union of Journalists at the Guardian and Observer this week, we are re-running an episode from earlier in the year. For more information please head to theguardian.com. We’ll be back with new episodes soon.. Help support our independent journalism at theguardian.com/sciencepod)