How Fast Are You Aging? Understanding the Dunedin Pace and the Power of Epigenetics - Episode 262
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In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden interviews Hannah Went, co-founder of TrueAge, a leading omics age company. They discuss the significance of epigenetics in understanding biological age, the predictive power of various aging clocks, and the advancements in measuring biological age through multi-omics approaches. The conversation also covers the impact of interventions like caloric restriction on aging metrics, the Dunedin Pace as a new metric for biological aging, and the complexity of aging as a multifactorial process. Went shares insights into the future of epigenetic research and the importance of actionable insights for health optimization.    For the audience:   * Use the code 'Podcast10' to get 10% OFF your order at our supplement store → https://gladdenlongevityshop.com/         Takeaways    * Epigenetic markers can predict chronological age with high accuracy.  * GrimAge is a new clock that estimates mortality risk.  * Multi-omics approaches provide a comprehensive view of aging.  * Caloric restriction significantly impacts biological age.  * Dunedin Pace measures the rate of biological aging.  * Aging is a complex, multifactorial process.  * Understanding what tests do not measure is crucial.  * New biomarkers for aging are being developed and validated.    Chapters    00:00 Introduction to Omics Age and TrueAge  04:12 The Evolution of Epigenetic Clocks  07:55 Integrating Lifestyle Factors in Omics Age Testing  10:14 Predicting Disease Risk and Mortality with Omics Age  13:27 Reversing Biological Age with Interventions  16:42 Actionable Insights from Omics Age Testing  26:30 Exploring the Impact of Caloric Restriction on Aging  29:08 Understanding the Dunedin Pace as a Measure of Biological Aging  33:32 The Complexity of Aging and the Limitations of Single Metrics  35:24 Epigenetic Biomarker Proxies: A Comprehensive Approach to Aging  43:59 Cell Reprogramming and its Implications for Aging  49:24 Goodbye    Learn more about TruAge and/or contact them:  Email: [email protected]   Website: https://www.trudiagnostic.com/   Facebook: https://www.facebook.com/TruDiagnostic/   Instagram: https://www.instagram.com/trudiagnosticofficial/   X: https://x.com/TruDiagnostic   YouTube: https://www.youtube.com/c/trudiagnostic   TikTok: https://www.tiktok.com/@trudiagnostic?is_from_webapp=1&sender_device=pc   LinkedIn: https://www.linkedin.com/company/trudiagnostic/     Reach out to us!   Website: https://gladdenlongevity.com/    Email: [email protected]    Facebook: https://www.facebook.com/Gladdenlongevity/   Instagram: https://www.instagram.com/gladdenlongevity/?hl=en    LinkedIn: https://www.linkedin.com/company/gladdenlongevity   YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw