cover of episode EP 149: Sequencing 33 million samples to support the UK’s COVID-19 response with Tony Cox, CEO of UK Biocentre

EP 149: Sequencing 33 million samples to support the UK’s COVID-19 response with Tony Cox, CEO of UK Biocentre

2024/8/29
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The Genetics Podcast

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Shownotes Transcript

0:00 Intro to The Genetics Podcast01:00 Welcome to Tony02:00 What Tony was expecting going into the role of CEO at UK Biocentre, and how the COVID-19 pandemic changed his plans03:38 Receiving a phone call from the UK government in March 2020 asking the UK Biocentre to stop all of its projects and focus on sequencing COVID-19 samples05:12 The UK Biocentre’s scale-up process, including how many samples the UK Biocentre sequenced over the course of the pandemic09:30 The biggest changes that enable sequencing to scale from 1,000 to 100,000 samples per day13:33 What Tony has learned about how best to implement an accelerated, unified effort to deliver for public health16:17 The organization’s current focus on large-scale genomics projects such as Our Future Health18:50 The challenges which need to be overcome to deliver the Our Future Health project22:19 How UK Biocentre preserves it samples and the logistical challenges involved24:04 The types of projects that involve the largest-scale levels of sampling and storage28:12 Figuring out how to integrate a preventive, sample-based approach to healthcare within the parameters of cost and scale  29:27 The future proofing of sample storage techniques31:33 The importance of consent structure and how to utilize long-term serial sampling33:24 The upcoming technology or projects that most excite Tony36:19 Closing remarksFind out moreukbiocentre.comourfuturehealth.org.uk)