0:00 Intro to The Genetics Podcast01:00 Welcome to Jakob and background on Pheiron02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up5:24 Jakob’s excitement and inspiration around the power and potential of machine learning07:07 Cardiology and heart failure as an example of the gap between where research needs to be compared to where it is today10:52 Why creating the GPS for identifying patients at increased risk of disease is a challenge on multiple fronts12:42 How Pheiron’s approach and specificity is opening up the possibility of identifying highly-relevant patients and running clinical trials at greater pace17.35 How testing potential treatments in a highly-specific population affects the design of Phase 3 clinical trials21:19 The types of data required to build Pheiron’s GPS - from population scale insights to deep analysis within subgroups23:48 Whether there is a shortage of healthcare systems with robust research arms looking to participate in such collaborations27:30 Working with patients to build a collaborative commitment to data sharing28:22 Making the decision to start Pheiron rather than continue working in medicine or research30:38 Core learnings from building a company from the ground up31:35 What Jakob is currently most focused on and what he hopes to achieve with Phieron in the immediate future34:40 Closing remarksPlease consider rating and reviewing) us on your chosen podcast listening platform!Find out more:www.pheiron.com)Find Jakob on Twitter) (X)
