cover of episode EP 120: Exploring the frontiers of gene therapy and AAVs with Dr. Nicole Paulk, CEO and Founder of Siren Biotechnology

EP 120: Exploring the frontiers of gene therapy and AAVs with Dr. Nicole Paulk, CEO and Founder of Siren Biotechnology

2024/2/1
logo of podcast The Genetics Podcast

The Genetics Podcast

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Shownotes Transcript

0:00 Introduction to Dr. Nicole Paulk, a pioneer in AAV research and the founder of Siren Biotechnology0:50 The moments that shaped Nicole’s career path and her passion for gene therapy and AAV research9:20 Nicole’s academic research career and her transition from academia to the biotech industry23:00 The story behind the founding of Siren Biotechnology30:11 Major challenges and breakthroughs in developing Universal AAV Immuno-Gene Therapy and vectorising cytokines.36:00 Long-term impacts of using gene editing to target oncogenes37:30 Challenges of 2023 in the startup field and Nicole’s expectations for 202442:00 Academia vs. Industry: Research processes and the pace of grant writing and innovation46:40 Closing remarks