cover of episode #311 ‒ Longevity 101: a foundational guide to Peter's frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more

#311 ‒ Longevity 101: a foundational guide to Peter's frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more

2024/7/29
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Peter Attia: 本期节目讨论了长寿的定义,以及如何将长寿科学转化为可供所有人理解的内容。他阐述了寿命、健康寿命和临界十年等基本概念,并讨论了四大死因及其预防,以及他长寿工具包中的五大策略,以改善寿命和健康寿命。他还解释了医学1.0、2.0和3.0的演变,以及如何预防动脉粥样硬化性疾病、癌症和神经退行性疾病。他强调了代谢疾病的影响,以及即使在老年也开始关注长寿并不算太晚。最后,他概述了长寿工具包的五个组成部分:运动、营养、睡眠、药物和补充剂以及情绪健康。

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Longevity is a function of both lifespan and healthspan. While lifespan is simply how long you live, healthspan encompasses physical, cognitive, and emotional well-being. Optimizing both is crucial for a fulfilling life.
  • Longevity is made up of lifespan and healthspan.
  • Healthspan has physical, cognitive, and emotional components.
  • Improving healthspan often improves lifespan as well.

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In this special episode, Peter provides a comprehensive introduction to longevity, perfect for newcomers or those looking to refresh their knowledge. He lays out the foundational concepts of lifespan, healthspan, and the marginal decade. Additionally, Peter discusses the four main causes of death and their prevention, as well as detailing the five key strategies in his longevity toolkit to improve lifespan and healthspan. Detailed show notes provide links for deeper exploration of these topics, making it an ideal starting point for anyone interested in understanding and improving their longevity.

We discuss:

  • Key points about starting exercise as an older adult [2:45];
  • Overview of episode topics and structure [1:45];
  • How Peter defines longevity [3:45];
  • Why healthspan is a crucial component of longevity [11:15];
  • The evolution of medicine from medicine 1.0 to 2.0, and the emergence of medicine 3.0 [15:30];
  • Overview of atherosclerotic diseases: the 3 pathways of ASCVD, preventative measures, and the impact of metabolic health [26:00];
  • Cancer: genetic and environmental factors, treatment options, and the importance of early and aggressive screening [33:15];
  • Neurodegenerative diseases: causes, prevention, and the role of genetics and metabolic health [39:30];
  • The spectrum of metabolic diseases [43:15];
  • Why it’s never too late to start thinking about longevity [44:15];
  • The 5 components of the longevity toolkit [46:30];
  • Peter’s framework for exercise—The Centenarian Decathlon [47:45];
  • Peter’s nutritional framework: energy balance, protein intake, and more [58:45];
  • Sleep: the vital role of sleep in longevity, and how to improve sleep habits [1:08:30];
  • Drugs and supplements: Peter’s framework for thinking about drugs and supplements as tools for enhancing longevity [1:13:30];
  • Why emotional health is a key component of longevity [1:17:00];
  • Advice for newcomers on where to start on their longevity journey [1:19:30]; and
  • More.

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