cover of episode A virus that could heal people

A virus that could heal people

2021/4/28
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Unexplainable

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Nicola Twilley
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Noam Hassenfeld
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Noam Hassenfeld: 本期节目讨论了抗生素耐药性日益严重的问题,以及噬菌体疗法作为潜在解决方案的可能性。节目中介绍了抗生素耐药性感染的严重性和日益增长的死亡人数,强调了寻找替代疗法的紧迫性。同时,节目也探讨了噬菌体疗法的局限性,例如噬菌体的特异性以及对噬菌体了解有限等。 Nicola Twilley: 详细解释了什么是噬菌体,以及噬菌体如何攻击细菌。她描述了噬菌体疗法的基本原理,即利用噬菌体杀死感染人体的细菌。她还介绍了噬菌体疗法的实际应用,包括寻找合适的噬菌体以及将噬菌体用于治疗患者的案例。此外,她还讨论了噬菌体疗法面临的挑战,例如噬菌体的特异性、研究的滞后以及噬菌体潜在的危险性。她指出,虽然噬菌体疗法具有巨大的潜力,但要将其广泛应用于临床,还需要进行大量的研究。 Noam Hassenfeld: 节目中还探讨了噬菌体研究的历史,以及为什么西方国家对噬菌体研究起步较晚。节目指出,由于噬菌体研究与纳粹和共产主义的联系,以及抗生素的简单易用性,导致噬菌体研究在西方国家长期被忽视。节目还讨论了噬菌体疗法的局限性,以及如何克服这些局限性。最后,节目强调了对噬菌体进行研究的重要性,不仅是为了应对抗生素耐药性危机,也是为了更好地理解整个生物生态系统。

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Chapters
The episode discusses the severe issue of antibiotic resistance, highlighting its classification as the greatest and most urgent global risk by the United Nations in 2016. It emphasizes the increasing mortality rates due to drug-resistant infections and the role of human practices in accelerating bacterial resistance to antibiotics.

Shownotes Transcript

In 2016, the UN declared antibiotic-resistant bacteria the “greatest and most urgent global risk.” Our best hope just might be phages, or viruses that attack bacteria. Phages’ potential is enormous, but so is everything we don’t know about them.

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