Assad fled to Russia with his family as rebel forces swept into Damascus, marking the end of his 54-year reign in Syria.
Biden called it a 'moment of historic opportunity' but also warned of potential risks, particularly from ISIS taking advantage of the vacuum.
Syrians celebrated across the country, with many feeling dazed and incredulous after 54 years of Assad's rule and 13 years of civil war.
The U.S. carried out large airstrikes on Islamic State bases in central Syria, targeting 75 targets to prevent ISIS from taking advantage of the turmoil.
Trump said Syria is not a U.S. problem and that the U.S. should not get involved, suggesting to let the situation play out.
Both Iran and Russia suffered significant setbacks as they were major backers of Assad. Iran, in particular, lost a key ally and a bridge for shipping weapons to Hezbollah in Lebanon.
Trump plans to address dreamers with a legislative solution and aims to end birthright citizenship, potentially requiring a constitutional amendment. He also reiterated his intent to start mass deportations, beginning with criminals.
Trump suggested that members of the committee should go to jail, though he did not specify for what, and he plans to consider pardons for those convicted of crimes related to January 6th on a case-by-case basis.
After 54 years, the Assad's brutal reign in Syria is over. Bashar al-Assad fled to Russia with his family as rebel forces swept into the capital of Damascus. President Biden called the fall of the Assad regime a "moment of historic opportunity." But he also warned of the potential risks. And President-elect Trump gave his first network TV interview since winning the election. *Want more comprehensive analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter).Today's episode of Up First was edited by James Hider, Andrew Sussman, Roberta Rampton, HJ Mai and Alice Woelfle. It was produced by Ziad Buchh, Nia Dumas and Kaity Kline. We get engineering support from Stacey Abbott and our technical director is Carleigh Strange.*Learn more about sponsor message choices: podcastchoices.com/adchoices)NPR Privacy Policy)