Fentanyl is the most dangerous substance because it is far more potent than heroin or cocaine, with a tiny amount being enough to cause an overdose. It has also infiltrated various drug supplies, making it highly lethal.
Fentanyl has adulterated many drugs, including those commonly used in the rave scene like LSD and ecstasy, making the scene much more dangerous for young people who may unknowingly consume fentanyl-laced drugs.
Chinese labs produce fentanyl and its analogs, often tweaking the chemical structure to stay within legal limits. These labs export precursor chemicals to Mexico, where cartels finish the production and distribute the drug to the U.S.
Fentanyl is more addictive and dangerous than heroin because it requires users to take it multiple times a day to avoid withdrawal, leading to higher overdose risks. Heroin, while dangerous, provides a longer-lasting effect.
Fentanyl addiction is primarily driven by the drug's ability to provide intense pleasure, but it also creates a physical dependency that requires users to take more to avoid withdrawal symptoms.
Police officers overdosing from touching fentanyl is likely a mass psychogenic event. The belief that touching fentanyl can cause overdose leads to psychological symptoms that mimic overdose, even when no actual fentanyl is present.
Combining fentanyl with benzodiazepines like Xanax or alcohol is extremely dangerous. These combinations slow down breathing, increasing the risk of fatal overdose.
Fentanyl is smuggled into the U.S. by cartel-affiliated individuals, often hidden in vehicles crossing the border. The drug is then distributed across the country from major transshipment points like Los Angeles and Phoenix.
A fentanyl shortage has occurred due to pressure on the Sinaloa cartel in Mexico, which was convinced by local authorities to stop trafficking fentanyl in certain areas, leading to a temporary reduction in supply.
The most effective approach is to focus on helping those already addicted, using proven treatments like naltrexone, methadone, and buprenorphine, rather than trying to stop the supply of drugs at the border.
In 2023, 107,543 Americans died from an overdose—over 75 thousand of those overdosed from fentanyl. This is almost double the number of people who died in car accidents or from gun homicides that year.
Fentanyl has been cut into heroin for years, but now is often mixed into meth and cocaine, fueling rising death counts for those drugs, a troubling development, considering that Americans are much more likely to try meth and cocaine than heroin.
In Canada, the numbers are similarly astronomical, and fentanyl deaths have marched upward in Australia and many European countries as well. Ten years ago, fentanyl and its analogues overtook heroin to become the deadliest drug in Sweden.
“Fentanyl is the game changer,” Special Agent in Charge James Hunt of the US Drug Enforcement Administration (DEA) told Vice News. “It’s the most dangerous substance in the history of drug tracking. Heroin and cocaine pale in comparison to how dangerous fentanyl is.”
Ben Westhoff is a best-selling investigative journalist focused on drugs, culture, and poverty. His book Fentanyl, Inc.: How Rogue Chemists Created the Deadliest Wave of the Opioid Epidemic is the bombshell first book about fentanyl. Since its publication, Westhoff has advised top government officials on the fentanyl crisis, including from the White House Office of National Drug Control Policy, U.S. Senate and House of Representatives, the U.S. embassy in Beijing, and the U.S. State Department.